You don't need to any extra work. They are plug and play modules with internal regulators etc to get it up and running. You happily connect it to pixhawk and enjoy flying.
One thing to remember is if it says GPS for pixhawk that means it will work with pixhawk without any mods or any manual work from your end.
I wanted to use it with omnibus f4 pro v2, where the UART voltage is 5v. For now I am using a 5v to 3.3v step down module.